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目的探讨多层螺旋计算机(CT)断层扫描动态增强扫描联合电子鼻咽镜检查在鼻咽癌早期诊断中的应用效果。方法选取2013年3月至2015年8月间广东医学院附属中山医院收治的39例鼻咽癌患者,根据患者主要临床症状分为Ⅰ组(颅神经损伤组)、Ⅱ组(颈部淋巴结肿大组)及Ⅲ组(耳鼻症状组),3组患者均给予多层螺旋CT动态增强扫描及电子鼻咽镜检查,并分析联合检查结果。结果 3组患者多层螺旋CT动态增强扫描及电子鼻咽镜检查阳性率间差异无统计学意义(P>0.05)。多层螺旋CT动态增强扫描显示Ⅱ组患者咽旁间隙受侵率明显高于其他两组,差异有统计学意义(P<0.05)。Ⅲ组患者颅底受侵袭率明显高于其他两组,差异有统计学意义(P<0.05)。复发患者多层螺旋CT动态增强扫描假阳性率高于电子鼻咽镜检查结果,差异有统计学意义(P<0.05)。结论多层螺旋CT动态增强扫描联合电子鼻咽镜能准确诊断鼻咽癌及复发病例,在鼻咽癌早期诊断中具有重要的临床应用价值。
Objective To investigate the effect of multislice spiral computed tomography (CT) dynamic contrast-enhanced tomography combined with electronic nasopharyngoscopy in nasopharyngeal carcinoma (NPC) early diagnosis. Methods Thirty-nine patients with nasopharyngeal carcinoma admitted to Zhongshan Hospital Affiliated to Guangdong Medical College from March 2013 to August 2015 were divided into group Ⅰ (cranial nerve injury group) and group Ⅱ (cervical lymph node enlargement) according to the main clinical symptoms of the patients. Large group) and group Ⅲ (group of otolaryngology). Three groups of patients were given multi-slice spiral CT dynamic contrast-enhanced scanning and electronic nasopharyngoscopy, and the results of joint examination were analyzed. Results There was no significant difference between the three groups in dynamic enhanced CT scan and electronic nasopharyngoscopy (P> 0.05). Multi-slice spiral CT dynamic contrast-enhanced scanning showed that the invasion rate of parapharyngeal space in group Ⅱ was significantly higher than that in other two groups (P <0.05). The invasion rate of skull base in group Ⅲ was significantly higher than that in other two groups (P <0.05). The false-positive rate of multislice CT dynamic contrast-enhanced scanning in relapsed patients was higher than that of electronic nasopharyngoscopy (P <0.05). Conclusion Multi-slice spiral CT dynamic enhanced scanning combined with electronic nasopharyngoscopy can accurately diagnose nasopharyngeal carcinoma and recurrent cases and has an important clinical value in the early diagnosis of nasopharyngeal carcinoma.