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人轮状病毒主要引起婴幼儿腹泻,所产生的血清抗体不能防御再感染。动物研究表明肠内局部抗体对保护再感染起重要作用,直至产后9个月的人奶中,尚可发现有分泌型轮状病毒IgA抗体,具保护作用。粪便中轮状病毒可在肠内发生抗体反应包括特异IgG和IgA的产生,当粪便中存在着轮状病毒时,多同时有IgA,但IgA本身并不能影响排毒期或腹泻期之长短。由轮状病毒诱发肠胃炎的儿童往往伴有呼吸道症状,并引起了许多学者的注意。但迄今
Human rotavirus mainly causes diarrhea in infants and young children, and the produced serum antibodies can not prevent reinfection. Animal studies have shown that the local intestinal antibodies play an important role in the protection of re-infection, until 9 months postpartum human milk, can still be found secreting rotavirus IgA antibodies, with a protective effect. Rotavirus in the faeces can produce antibody reactions in the intestine including specific IgG and IgA production. When there is rotavirus in the stool, more rotavirus is IgA at the same time, but IgA itself can not affect the detoxification period or the diarrhea period. Children with gastroenteritis induced by rotavirus often have respiratory symptoms and have drawn the attention of many scholars. But so far