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目的探讨婴幼儿社区获得性肺炎支原体(MP)肺炎的临床特征。方法对228例婴幼儿肺炎患儿血清采用ELISA法进行肺炎支原体抗体(MP-IgM)检测,MP-IgM阳性为MP感染组,MP-IgM阴性为对照组,并进行比较分析。结果感染组与对照组发病年龄差异有高度统计意义(P<0.01),发病季节无明显差异(P>0.05)。2组患儿均有咳嗽、喘鸣及呼吸困难,感染组高热、肺部X线片状阴影、C反应蛋白(CRP)阳性、WBC升高、肺外并发症等均高于对照组,差异均有高度统计意义(P<0.01)。结论 MP感染的婴幼儿肺炎以高热为主,且持续时间较长;WBC和CRP增高,肺部X线有肺气肿伴单侧片状阴影;肺外表现多见。对高度怀疑MP感染的患儿,应及时做MP抗体的检查以确诊。
Objective To investigate the clinical characteristics of community-acquired Mycoplasma pneumoniae (MP) pneumonia in infants and young children. Methods Serum samples of 228 infants and children with pneumonia were detected by ELISA for MP-IgM, MP-IgM was positive for MP and MP-IgM was negative for comparison. Results There was a significant difference in the age of onset between the infection group and the control group (P <0.01). There was no significant difference in onset season (P> 0.05). Both groups had cough, wheezing and dyspnoea, high fever in the infection group, pulmonary X-ray shadow, positive CRP, increased WBC and extra-pulmonary complications were higher than those in the control group All were highly statistically significant (P <0.01). Conclusion Infants and young children with MP infection are characterized by high fever and long duration, with increased WBC and CRP, pulmonary emphysema with unilateral lamellar shadow, and extrapulmonary manifestations. For patients with a high suspicion of MP infection, MP antibodies should be promptly diagnosed.