论文部分内容阅读
[目的]探讨河北农村居民人群中幽门螺旋杆菌(Helicobacter pylori,Hp)在家庭内感染情况。[方法]采用整群抽样调查方法,在河北遵化市下属两农村,以家庭为单位进行入户调查居民Hp感染情况,共调查人数735人,男性320人,女性415人,年龄在6～86岁之间,平均年龄为37.5岁。所有被调查者均采集静脉血检测HpU-IgG抗体,确定是否感染Hp。[结果]735例被调查者中Hp总感染率为67.35%,不同年龄组Hp感染情况不同(χ2=24.7789,P=0.0004);但性别间差异无统计学意义(χ2=0.3065,P﹥0.05)。通过二项分布拟和优度检验,Hp感染的家庭分布符合二项分布(χ2=6.6987,P﹥0.05),在理论分布上未发现Hp感染的家庭聚集性分布倾向,但夫妻之间的Hp感染情况一致(χ2=1.373,P﹥0.05),符合率为65.50%,双亲感染家庭儿童的Hp感染率为65.96%,高于双亲未感染家庭儿童的Hp感染率31.58%(χ2=6.714,P=0.0035)。密切接触家庭成员间Hp感染存在一定家庭聚集现象。[结论]该地区农村居民的Hp感染率为67.35%,男女性别间Hp感染差异无统计学意义。从分布上看家庭内Hp感染符合二项分布,无聚集性,但密切生活接触仍能增加家庭成员间感染的可能性。
[Objective] To investigate the domestic infection of Helicobacter pylori (Hp) among rural residents in Hebei province. [Methods] The cluster sampling method was used to investigate the Hp infection of residents among the households in Zunhua City, Hebei Province. The survey population was 735, including 320 males and 415 females, aged 6 ~ The average age of 86 years old is 37.5 years old. All respondents were collected venous blood samples detected HpU-IgG, to determine whether infected with Hp. [Results] The overall prevalence of Hp in 735 subjects was 67.35%, and Hp infection was different in different age groups (χ2 = 24.7789, P = 0.0004). However, there was no significant difference between sexes (χ2 = 0.3065, P> 0.05 ). The binomial distribution of Hp infection was consistent with binomial distribution (χ2 = 6.6987, P> 0.05) by binomial distribution goodness-of-fit test and no distribution of Hp-infected familial aggregation was found in the theoretical distribution. However, Hp (Χ2 = 1.373, P> 0.05). The coincidence rate was 65.50%. The infection rate of Hp was 65.96% in the children of parents infected with HIV, and the infection rate of Hp was 31.58% higher than those of uninfected parents (χ2 = 6.714, P = 0.0035). Hp infection in close contact with family members there is a certain degree of family aggregation. [Conclusion] The Hp infection rate of rural residents in this area was 67.35%. There was no significant difference in Hp infection between male and female. From the distribution point of view Hp infection in the family consistent binomial distribution, no aggregation, but close contact with life can still increase the possibility of infection among family members.