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卡氏肺囊虫能通过空气途径可从一种动物传至另一种动物,但其在人群中的传播途径仍不清楚。一般认为,卡氏肺囊虫感染具有特定的宿主。本研究对一母亲和同期发生肺炎的婴儿,其呼吸道样本中的卡氏肺囊虫进行基因测试并进行了对比。 母亲为25岁非洲黑人,既往健康。足月男婴于出生31天时诊断为间质性肺炎,34天开始出现呼吸衰竭,支气管肺泡灌洗液(BAL)检出卡氏肺囊虫,血中检出HIV-1型抗体,随后HIV-1 RNA亦阳性,HIV-1 RNA水平为426 460拷贝/mL。CD4~+T淋巴细胞计数为总数的32％,绝对计数为1997。接受卡氏肺囊虫肺炎的治疗后,患儿痊愈,随访17个月后仍然正常,CD4~+计数为2929/μL,占总数的
Pneumocystis carinii can pass through the air route from one animal to another animal, but its transmission in the crowd is still not clear. It is generally accepted that Pneumocystis carinii infection has a specific host. In this study, genetic testing and comparison of a Pneumocystis carinii in a respiratory sample of a mother and an infant with pneumonia were performed. The mother is a 25 year-old black african, past health. Full-term infants were diagnosed with interstitial pneumonia at day 31 of birth, respiratory failure at day 34, pneumocystis carinii in bronchoalveolar lavage (BAL), detection of HIV-1 antibodies in blood, and subsequent HIV -1 RNA was also positive with HIV-1 RNA level of 426 460 copies / mL. CD4 ~ + T lymphocyte count for the total number of 32%, the absolute count of 1997. After receiving the treatment of Pneumocystis carinii pneumonia, the children were cured and remained normal after 17 months of follow-up. The CD4 ~ + count was 2929 / μL, accounting for the total