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报告 5 3例多发性硬化 (MS)临床和磁共振成像 (MRI)的相关性。根据 5 3例MS临床表现 ,病灶定位有 12 4个 ,其中大脑 6 9个 ,小脑 11个 ,脑干 2 1个 ,视神经 2 3个。在脑MRI上显示病灶总数为 494个 ,分布在大脑半球双侧白质区 430个 ,底节 2 0个 ,丘脑 6个 ,脑干 17个 ,小脑 2 1个。其中 ,在大脑的亚临床病灶数 387个 ,占 84 87% ,小脑的亚临床病灶 10个 ,占 47 6 2 %。脑干和视神经未发现亚临床病灶。从临床定位病灶数分析 :临床定位病灶检出 5个者 2例 ,4个者 2例 ,3个者 18例 ,2个者 2 3例 ,1个者 8例。脑MRI病灶数分析 :显示 1个病灶者 3例 ,2～ 5个者 2 1例 ,6～ 10个者 17例 ,11～ 2 0个者 5例 ,2 1～ 30个者 5例 ,30个以上者 2例。通过相关分析 ,本组 5 3例MS的临床定位病灶数与脑MRI病灶数两者之间的相关系数γ为零。表明在脑MRI上MS病灶数与临床定位数有相当的差异 ,即MRI上病灶数远远超过临床定位病灶数 (494/ 12 4) ,约 4∶1。发现亚临床病灶数共 370个 ,占 74 90 % ,反映出MRI有较多的临床上不被发现的亚临床病灶
Report of 53 cases of multiple sclerosis (MS) clinical and magnetic resonance imaging (MRI) correlation. According to the clinical manifestations of 53 cases of MS, there were 12 4 lesions, of which 69 were brain, 11 were cerebellum, 21 were brain stem and 23 were optic nerve. The brain MRI showed a total of 494 lesions, located in the bilateral hemispheric white matter 430, 20 at the base, 6 of the thalamus, 17 of the brain stem and 21 of the cerebellum. Among them, there were 387 subclinical lesions in the brain, 84 87%, and 10 subclinical lesions in the cerebellum, accounting for 47 6 2%. Subclinical lesions were not found in the brainstem and optic nerve. From the clinical localization of the number of lesions: clinical localization of lesions were detected in 5 cases in 2 cases, 4 in 2 cases, 3 in 18 cases, 2 cases in 23 cases, 1 case in 8 cases. Cerebral MRI analysis of the number of lesions: There were 3 lesions in 1 lesions, 21 lesions in 2 ~ 5 lesions, 17 lesions in 6-10 lesions, 5 lesions in 11 ~ 20 lesions, 5 lesions in 21 ~ 30 lesions, 30 More than 2 cases. By correlation analysis, the correlation coefficient γ between the number of clinical localization lesions and the number of brain MRI lesions in 53 cases of MS in this group was zero. It showed that the number of MS lesions on the brain MRI was quite different from the clinical localization. The number of lesions on MRI far exceeded the number of clinical lesions (494/124), about 4: 1. A total of 370 subclinical lesions were found, accounting for 74.90%, reflecting the presence of more clinically undetected subclinical lesions in MRI