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当两个或两个以上的化合物,其结构的区别仅在于组成原子的空间排列不同时,这些化合物称为立体异构体。若两个异构体对偏振光的偏转方向相反而旋光度相等则称为对映体。对映体互为镜象关系时为手征性化合物。通常,由化学合成方法制得的手征化合物,往往都是外消旋体,而天然化合物则常是构形一定的手征化合物。人们已知,不同构形的旋光异构体,其生理活性(包括药理和营养作用等)、生物活性、毒性、香味、稳定性等可有很大的差别,如青霉素,在八个异构体中
When two or more compounds differ only in the arrangement of the atoms in the space, the compounds are termed stereoisomers. If two isomers of polarized light on the opposite direction of rotation and rotation is equal to the enantiomer. Enantiomers are chiral compounds when mirroring each other. In general, chiral compounds prepared by chemical synthesis are often racemic, whereas natural compounds are often chiral compounds with a well-defined configuration. It is known that the optical isomers of different configurations vary greatly in their biological activity (including pharmacological and nutritional effects, etc.), biological activity, toxicity, scent, stability and the like, such as penicillin, Body