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已知金属离子影响许多抗菌素的作用,一些作者指出在弱酸性环境中铜催化青霉素水解为无活性的青霉铜酸。放置CUuT—IUD妇女的宫颈粘液(尤其在增殖期宫颈粘液)中含有较高浓度的铜离子,
It is known that metal ions affect the action of many antibiotics and some authors indicate that copper catalyzes the hydrolysis of penicillin to inactive penicillinic acid in a mildly acidic environment. Cervical mucus placed on CUuT-IUD women (especially in proliferating cervical mucus) contained a higher concentration of copper ions,