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目的 观察前部缺血性视神经病变 (anterior ischemic optic neuropathy,AION)患者 2 4h动态血压、心率变化特征。 方法 分别对 AION和与其性别、年龄相匹配的无 AION对照组患者各 5 0例进行 2 4h血压、心率测量 ,并绘出由夜间 (2 3:0 0～ 5 :0 0 )到白天 (6 :0 0～ 2 2 :0 0 )的变化曲线。 结果 两组患者之间白天的血压、心率比较差异无显著性意义 (P>0 .0 5 ) ,白天血压、心率均高于夜间 (t=3.6 3,3.16 ;P<0 .0 5 )。夜间 AION组血压、心率低于对照组 (t=3.82 ,1.77;P<0 .0 1,0 .0 5 ) ,2 :0 0～ 7:0 0血压 ,尤其舒张压 AION组低于对照组 (P<0 .0 1) ,AION组心率于 2 :0 0～ 5 :0 0低于对照组 (女 P<0 .0 5 ,男 P<0 .0 1) ,夜间到白天的血压上升曲线 AION组呈现缓慢的、波动较大的上升曲线 ,而对照组则为急剧的、平稳的上升曲线。 结论 AION患者存在着对血压调节的某种缺陷 ;2 :0 0～ 7:0 0血压、心率的低点可能是 AION发生的易感时段。
Objective To observe the changes of ambulatory blood pressure and heart rate at 24 hours in patients with anterior ischemic optic neuropathy (AION). Methods Blood pressure and heart rate were measured at 24 hours in 50 patients with AION who did not receive AION and matched with their age and gender respectively. The blood pressure and heart rate were measured from 0 to 5: : 0 0 ~ 2 2: 0 0) curve. Results There were no significant differences in daytime blood pressure and heart rate between the two groups (P> 0.05). The blood pressure and heart rate during the day were higher than those at night (t = 3.6, 3.16; P <0.05). Nighttime blood pressure and heart rate in AION group were lower than those in control group (t = 3.82, 1.77; P <0.010,05), and blood pressure, especially diastolic blood pressure in AION group (P <0.01). The heart rate of AION group was lower than that of the control group (P <0.05, P <0.01) at 2: 0 0 ~ 5: 0 0, and the nocturnal to daytime blood pressure increased Curve AION showed a slow, fluctuating rise curve, while the control group showed a sharp, steady ascending curve. Conclusion AION patients have some defects in blood pressure regulation; 2: 0 0 ~ 7: 0 0 blood pressure, low heart rate may be susceptible to AION period.