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目的:对重症胰腺炎的相关死亡原因进行探讨和分析,并探究有效的治疗方案。方法:选取2008年3月-2014年3月宁化县医院收治的重症胰腺炎患者病例140例,研究患者的病期、病因以及治疗方法对患者死亡率的影响,并进行死亡因素统计分析。结果:本研究中重症胰腺炎患者死亡率为11.4%,死亡的主要原因有心衰、肾衰、真菌感染、中毒性休克、多器官衰竭(MOF)、急性呼吸窘迫综合征(ARDS)。其中重症胆源性胰腺炎74例,占本研究组52.9%;重症非胆源性胰腺炎66例,占本研究组47.14%。其中出现心力衰竭症状患者10例,死亡2例;出现肾功能衰竭症状患者9例,死亡2例;出现真菌感染症状患者25例,死亡3例;出现中毒性休克症状患者23例,死亡2例等。结论:重症胰腺炎的病情变化极为迅速,其临床病例变化也极为复杂,并发症较多,对人们的生命产生了严重的威胁,需要不断深入研究导致其死亡的因素,并制定有针对性的治疗方案,以提高治愈率。
Objective: To investigate and analyze the causes of death related to severe pancreatitis and to explore effective treatment options. Methods: One hundred and forty cases of severe pancreatitis admitted to Ninghua County Hospital from March 2008 to March 2014 were selected to study the influence of the duration, etiology and treatment of the patients on the mortality rate, and the statistical analysis of death factors. Results: The mortality rate of severe pancreatitis in this study was 11.4%. The main causes of death were heart failure, renal failure, fungal infection, toxic shock, multiple organ failure (MOF) and acute respiratory distress syndrome (ARDS). 74 cases of severe biliary pancreatitis, accounting for 52.9% of the study group; 66 cases of severe non-biliary pancreatitis, accounting for 47.14% of the study group. There were 10 patients with symptoms of heart failure and 2 deaths, 9 patients with renal failure symptoms and 2 deaths, 25 patients with fungal infection and 3 deaths, 23 patients with toxic shock symptoms and 2 deaths Wait. Conclusion: The condition of severe acute pancreatitis changes very rapidly. The clinical cases also have extremely complicated changes and more complications, posing a serious threat to people’s lives. Therefore, it is necessary to continuously study the factors leading to their death and make targeted Treatment options to increase cure rates.