论文部分内容阅读
为进一步了解前列腺增生症（ＢＰＨ）所致膀胱出口梗阻（ＢＯＯ）后逼尿肌超微结构的变化，以ＢＰＨ患者４０例，分两组为实验研究对象，并以１８例无下尿路梗阻的膀胱肿瘤病人作对照组。术前作相关检查，术中取膀胱前壁逼尿肌样本，作透视电镜观察。结果显示：对照组逼尿肌胞浆内肌丝及“致密区”排列整齐，线粒体无明显肿胀、变性；ＢＰＨ病人逼尿肌胞浆内肌丝及“致密区”排列紊乱，线粒体肿胀、变性。认为ＢＰＨ病人逼尿肌超微结构变化与其梗阻程度有关，线粒体的变性与膀胱功能的减退有密切关系。强调ＢＰＨ病人彻底解除梗阻的时间不宜过晚
In order to further understand the changes of detrusor ultrastructure after bladder outlet obstruction (BOO) induced by benign prostatic hyperplasia (BPH), 40 patients with BPH were divided into two groups for the experimental study, and 18 cases of urinary tract obstruction Of bladder cancer patients as control group. Related preoperative examination, intraoperative detrusor anterior bladder wall samples taken for observation by transmission electron microscopy. The results showed that in the control group, the myofilament and “compact zone” of detrusor cytoplasm were arranged neatly, the mitochondria had no obvious swelling and degeneration; the disorganized myofilament and “dense zone” of detrusor muscle of the BPH patients, the mitochondria swelling and degeneration . It is considered that the detrusor ultrastructure changes of BPH patients are related to the degree of obstruction, and the degeneration of mitochondria is closely related to the decrease of bladder function. BPH patients stressed the complete lifting of the obstruction should not be too late