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目的:观察非洛地平联合依那普利治疗高血压病合并糖尿病疗效。方法:将高血压病合并糖尿病120例,随机分为非洛地平联合依那普利治疗组(观察组)、非洛地平治疗组(对照1组)和依那普利治疗组(对照2组)各40例。观察组口服非洛地平5 mg/d+依那普利10 mg/d;对照1组口服非洛地平10 mg/d;对照2组口服依那普利20 mg/d;均服药2个月后比较3组疗效。结果:观察组总有效为90.0%,对照1组48.0%,对照2组53.0%;观察组总有效率非常显著高于对照1组及对照2组(P<0.01)。结论:非洛地平联合依那普利治疗高血压病合并糖尿病疗效优于单用非洛地平或依那普利。
Objective: To observe the efficacy of felodipine and enalapril in the treatment of hypertension complicated with diabetes mellitus. Methods: One hundred and twenty cases of hypertension complicated with diabetes mellitus were randomly divided into three groups: felodipine combined enalapril treatment group (observation group), felodipine treatment group (control group 1) and enalapril treatment group (control group 2 ) 40 cases each. The observation group received felodipine 5 mg / d plus enalapril 10 mg / d. The control group 1 received felodipine 10 mg / d. The control group 2 received enalapril 20 mg / d. After 2 months of treatment, Compare 3 groups curative effect. Results: The total effective rate was 90.0% in observation group, 48.0% in control group 1 and 53.0% in control group 2, and the total effective rate in observation group was significantly higher than that in control group 1 and control group 2 (P <0.01). Conclusion: Felodipine combined with enalapril treatment of hypertension with diabetes mellitus is superior to felodipine or enalapril alone.