论文部分内容阅读
目的:探讨小剂量乙胺丁醇所致中毒性视神经病变的诊断和防治。方法:通过对50例应用小剂量(15mg·kg~(-1)·d~(-1))乙胺丁醇治疗的结核病患者进行观察,并对其中发生视神经损害病例的临床表现和诊断进行分析,总结防治乙胺丁醇引起的视神经损害的有效方法。结果:50例中4例发生中毒性视神经病变,经血管扩张药、神经营养药治疗,视力、色觉和视野均恢复正常。结论:医生应警惕小剂量乙胺丁醇发生中毒性视神经病变的风险。用药过程中应定期,监测视功能,避免或减少视神经损害的发生。
Objective: To investigate the diagnosis and prevention of toxic optic neuropathy caused by ethambutol. Methods: Fifty patients with tuberculosis treated with ethambutol at low dose (15 mg · kg -1 · d -1) were observed and the clinical manifestations and diagnosis of optic nerve damage Analysis, summarize the effective method of prevention and treatment of ethambutol caused optic nerve damage. Results: In 50 cases of 4 cases of toxic optic neuropathy, vasodilators, neurotrophic drugs, visual acuity, color vision and visual field were returned to normal. CONCLUSIONS: Doctors should be alert to the risk of developing toxic optic neuropathy at low doses of ethambutol. Medication process should be regularly monitored visual function, to avoid or reduce the occurrence of optic nerve damage.