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目的探讨雌激素配伍孕激素在吸宫术后预防宫腔粘连的作用。方法选取2003~2013年在成都市计划生育指导所诊断为胚胎停育患者230例,分为A、B两组。A组(117例)吸宫术后当日给予口服戊酸雌二醇,后半周期加服醋酸甲羟孕酮,B组(113例)术后未服用雌、孕激素。对两组患者术后子宫内膜连续性差者行宫腔镜检查,了解宫腔粘连的发生情况。结果 A组术后子宫内膜连续性差者17例,宫腔粘连4例(3.4%);B组子宫内膜连续性差者41例,宫腔粘连24例(21.2%),两组差异有统计学意义(P<0.05)。结论吸宫术后立即用外源性雌激素配伍孕激素对防止宫腔粘连能起到一定的预防作用。
Objective To explore the effect of estrogen combined with progesterone in the prevention of intrauterine adhesions after aspiration. Methods From 2003 to 2013, 230 cases of embryo stop diagnosed by Family Planning Guidance Center of Chengdu were selected and divided into A and B groups. A group (117 cases) was given oral administration of estradiol valerate on the day after ejaculation, plus medroxyprogesterone acetate in the second half cycle, and group B (113 cases) did not take estrogen and progesterone after operation. Hysteroscopy in two groups of patients with poor continuity of the endometrium to understand the occurrence of intrauterine adhesions. Results In group A, there were 17 cases with poor endometrial continuity and 4 cases with intrauterine adhesions (3.4%). There were 41 cases with poor endometrial continuity and 24 cases with intrauterine adhesions (21.2%) in group B, there were statistically significant differences between the two groups Significance (P <0.05). Conclusions Epidural estrogen plus progesterone immediately after earthen abscess may play a preventive role in preventing uterine adhesions.