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目前认为原发性肾小球肾炎,发病机理是循环中免疫复合物或抗肾小球基膜抗体或肾组织中局部形成的免疫复合物而引起肾脏病变,最常见的致病因素是细菌、原虫和病毒感染.微小肾小球病变临床通常表现为明显的肾病综合征,占小儿原发性肾病综合征的70%,成人的15%,对皮质激素的疗效好。最近的用法是,小儿强的松2～2.5毫克/公斤/日,青少年1～1.5毫克/公斤/日(最大的剂量不超过80毫克/日)。清晨一次顿服,共4周,再接着用上述剂量的2/3,隔日晨服一次,4周。如果在每晨
Now that primary glomerulonephritis, the pathogenesis of circulating immune complexes or anti-glomerular basement membrane antibodies or renal tissue locally formed immune complexes caused by renal disease, the most common risk factors are bacteria, Protozoan and viral infections.Microspherical glomerular lesions are usually clinically manifested as nephrotic syndrome, accounting for 70% of children with primary nephrotic syndrome, 15% of adults, good effect on corticosteroids. The most recent usage is 2 to 2.5 mg / kg / day for pediatric prednisone and 1 to 1.5 mg / kg / day for adolescents (maximum dose not exceeding 80 mg / day). Dayton morning service, a total of 4 weeks, then followed by the dose of 2/3, morning service the next day, 4 weeks. If every morning