【摘 要】
：
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)-4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its che
【出 处】
：
Chinese Chemical Letters
论文部分内容阅读
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl)-4-oxo-4-[2-(lactobionylamido)ethylamido]butanoate 6 was synthesized. Its chemical structurewas characterized by IR, ESI-MS, C NMR, H NMR. Doxorubicin entrapped in the liposomes 13 1containing 10% mol/mol 6 was rapidly accumulated in liver and mainly uptake by parenchymalcells in mice.
A novel galactosylated cholesterol with mono-galactoside moiety, (5-cholesten-3-yl) -4-oxo-4- [2- (lactobionylamido) ethylamido] butanoate 6 was synthesized. Its chemical structure is characterized by IR, C NMR, H NMR. Doxorubicin entrapped in the liposomes 13 1containing 10% mol / mol 6 was rapidly accumulated in liver and mainly uptake by parenchymal cells in mice.
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