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本文分析了946例孕妇乙肝病毒血症与围产儿的关系,结果发现:①妊娠合并乙肝组其早产率为16.10％,是正常孕妇的3.87倍,围产儿病死率为39.68‰,是正常组的4.99倍;②妊娠合并乙肝组新生儿窒息率达9.92％,为单纯妊娠期肝损的3.67倍;③有无乙肝病毒感染对胎儿宫内生长发育无明显影响,但有无肝功能损害对胎儿生长有一定影响;④有乙肝病毒感染组其妊高征发生率、产后出血率均明显高于正常组,⑤HBsAg和HBeAg均阳性者其母婴传播率为83.23％,新生儿肝炎发病率为16.67％,对母血乙肝病毒血症阳性的新生儿予乙肝疫苗预防接种,随访6至12个月婴儿出现免疫抗体阳性率为70％。
This article analyzes the relationship between 946 pregnant women with hepatitis B viremia and perinatal children, the results found that: ① pregnant with hepatitis B premature birth rate was 16.10%, 3.87 times the normal pregnant women, perinatal mortality was 39.68 ‰, is the normal group 4.99 times; ② neonatal asphyxia in pregnancy with hepatitis B group was 9.92%, 3.67 times that of simple pregnancy; ③ with or without hepatitis B virus infection on fetal growth and development had no significant effect, but with or without liver damage to the fetus The incidence of PIH and the rate of postpartum hemorrhage were significantly higher than those in the normal group. (5) The rate of mother-to-infant transmission was 83.23% with HBsAg and HBeAg positive, and the incidence of neonatal hepatitis was 16.67 %, To newborns with positive maternal blood hepatitis B viremia vaccination against hepatitis B, 6 to 12 months follow-up of the baby immunized antibody positive rate of 70%.