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目的:了解云南省德宏州未婚孕产妇艾滋病流行趋势,探讨影响未婚孕产妇感染艾滋病病毒(HIV)的危险因素。方法:收集2005-2010年间进入德宏州各级医院和计划生育服务站就诊的未婚孕产妇的社会人口学、行为学和HIV感染信息,对HIV阳性者血清进行BED-捕获酶联免疫试验(BED-CEIA)以检测其是否系新近感染者。结果:德宏州2005-2010年间共调查12 742例未婚孕产妇,HIV感染率和新近感染率分别为0.71%和0.25%。2007年HIV感染率和新近感染率最高,分别为1.13%和0.86%。多因素logistic回归分析结果显示,缅甸籍(AOR:2.57;95%CI:1.13～5.84)未婚孕产妇HIV感染率较高,而高中/中专文化程度(AOR:0.19;95%CI:0.06～0.58)、“丈夫”/男朋友无吸毒史(AOR:0.18;95%CI:0.04～0.75)未婚孕产妇HIV感染率较低。结论:德宏州未婚孕产妇HIV感染率及新近感染率较高。缅甸籍、“丈夫”/男朋友吸毒史、文化水平低是导致未婚孕产妇感染HIV的高危因素。有必要加强未婚孕产妇人群艾滋病防控工作。
Objective: To understand the epidemiological trend of unmarried pregnant women in Dehong Prefecture of Yunnan Province and to explore the risk factors that affect uninfected pregnant women infected with HIV. Methods: The socio-demographic, behavioral and HIV infection information of unmarried pregnant women who visited hospitals and family planning service stations of Dehong Prefecture at all levels during 2005-2010 were collected. The serum of HIV-positive persons was tested for BED-capture enzyme-linked immunosorbent assay BED-CEIA) to detect if it is newly infected. Results: A total of 12 742 unmarried pregnant women were surveyed in Dehong during 2005-2010. The rates of HIV infection and recent infection were 0.71% and 0.25%, respectively. The highest rates of HIV infection and recent infection in 2007 were 1.13% and 0.86%, respectively. Multivariate logistic regression analysis showed that the prevalence of HIV infection among unmarried pregnant women was higher in Myanmar (AOR: 2.57; 95% CI: 1.13-5.84), while that in senior high school / secondary school (AOR: 0.19; 95% CI: 0.58), “husband” / boyfriend no history of drug abuse (AOR: 0.18; 95% CI: 0.04 ~ 0.75). Conclusion: The rate of HIV infection and the recent infection rate of unmarried pregnant women in Dehong Prefecture are higher. Burmese, “husband ” / boyfriend drug abuse history, low level of culture is the risk of HIV infection in unmarried pregnant women risk factors. It is necessary to strengthen AIDS prevention and control work for unmarried pregnant women groups.