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过去,胶原病的治疗主要用糖皮质激素、免疫抑制剂及非甾体类抗炎药。近几年来,随着免疫学的飞跃发展,对本病的发病基础有了进一步的认识,临床应用亦随之有了发展。随着IgE 依赖性变态反应机制的阐明,很快研制出了抗变态反应药,在日本更有其独到之处。从IgE依赖性变态反应的炎症理论出发,甾体类药物的应用也有了新的见解。现以系统性红斑狼疮(SLE)和支气管哮喘为例,概述其治疗进展。一、胶原病的治疗进展
In the past, the main treatment of collagen disease with glucocorticoids, immunosuppressive agents and non-steroidal anti-inflammatory drugs. In recent years, with the rapid development of immunology, the basis for the pathogenesis of this disease has been further understanding of the clinical application also will be developed. With the elucidation of the mechanism of IgE-dependent allergy, anti-allergy drugs were soon developed and more unique in Japan. Based on the theory of inflammation of IgE-dependent allergy, there are new insights into the use of steroids. Now with systemic lupus erythematosus (SLE) and bronchial asthma, for example, outlined its treatment progress. First, the progress of the treatment of collagen disease