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目的探讨甲状腺功能减退与不良孕史的相关性及孕期甲状腺功能减退筛查的意义。方法选取2010年10月-2011年8月期间在我院门诊就诊的生育年龄妇女共243例,采用化学发光(CIA)进行甲状腺功能激素系列(TSH、FT4、TPOAb)测定。结果不良孕史中甲状腺功能低下所占比例明显高于无不良孕史组;亚临床甲状腺功能低下在临床上发生率相对较高。结论甲状腺功能减低与不良孕史有明显相关性;要重视亚临床甲状腺功能低下的发生;进行孕期甲状腺功能筛查很有必要。
Objective To investigate the correlation between hypothyroidism and poor pregnancy history and the significance of thyroid hypothyroidism during pregnancy screening. Methods A total of 243 reproductive-age women in our hospital from October 2010 to August 2011 were selected for thyroid function hormone series (TSH, FT4, TPOAb) determination by chemiluminescence (CIA). Results The proportion of hypothyroidism in the history of adverse pregnancy was significantly higher than that in the group without adverse pregnancy; the clinical incidence of subclinical hypothyroidism was relatively high. Conclusions There is a significant correlation between hypothyroidism and poor pregnancy history; attention should be paid to the occurrence of subclinical hypothyroidism; thyroid function screening during pregnancy is necessary.