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目的：探讨视网膜下间隙的免疫学特点。方法：将ＤＭＥＭ，同源视网膜，ＤＢＡ／２鼠视网膜加或不加完全福氏佐剂（ＣＦＡ）和人外周血单个核细胞（ＰＢＭＣ）分别植入ＢＡＬＢ／Ｃ鼠的视网膜下间隙，２周后检测迟发型超敏反应（ＤＴＨ）、细胞毒性Ｔ淋巴细胞（ＣＴＬ）的特异杀伤率及行眼组织病理学检查。结果：实验组ＤＴＨ与阴性对照ＤＭＥＭ组无显著性差异，但ＣＴＬ的特异杀伤率与ＤＭＥＭ组存在显著性差异。ＤＢＡ／２鼠视网膜移植物存活。人ＰＢＭＣ移植发生免疫排斥反应。结论：视网膜下间隙移植，发生一定限度的免疫赦免
Objective: To investigate the immunological characteristics of subretinal space. Methods: The subretinal space of BALB / C mice was implanted with DMEM, homologous retina, DBA / 2 mouse retina with or without complete Freund’s adjuvant (CFA) and human peripheral blood mononuclear cells (PBMC) After the detection of delayed type hypersensitivity (DTH), cytotoxic T lymphocytes (CTL) specific killing rate and pathological examination. Results: There was no significant difference between DTH and negative control DMEM group, but there was significant difference between CTL specific killing rate and DMEM group. DBA / 2 retinal graft survival. Immune rejection occurs in human PBMC transplantation. Conclusion: Subretinal space transplantation, a limited number of immune pardon