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采用原子吸收光谱技术测定清醒兔脊髓缺血２０ｍｉｎ再灌流不同时间的Ｎａ、Ｋ、Ｃａ、Ｍｇ和Ｆｅ含量，并用干湿法测定脊髓水含量。在再灌流１２～４８ｈ，Ｌ７、Ｌ６和Ｌ５发生严重水肿，Ｌ４在４８ｈ也发生水肿；Ｌ４的Ｎａ含量在再灌流４ｄ、Ｃａ含量在再灌流７ｄ才显著升高，提示Ｎａ储留、水肿和Ｃａ超载是脊髓继发损伤过程中的病理表现。Ｌ４Ｋ含量在缺血２０ｍｉｎ下降不显著，但再灌流２ｈ即进行性下降，持续至７ｄ；Ｌ４Ｍｇ在缺血２０ｍｉｎ即显著下降，再灌流１２ｈ恢复，２４～４８ｈ再次下降；表明Ｋ和Ｍｇ含量下降与脊髓缺血性继发损伤和功能障碍密切相关。
The content of Na, K, Ca, Mg and Fe in spinal cord of conscious rabbits at 20 min after reperfusion was measured by atomic absorption spectrometry. The water content of spinal cord was measured by dry and wet method. At 12-48 hours after reperfusion, severe edema occurred on L7, L6 and L5 and edema occurred on L4 at 48th hour. The content of Na in L4 was significantly increased at 7 days after reperfusion, suggesting that Na retention, edema and Ca overload is a pathological manifestation of secondary spinal cord injury. The content of L4K was not significantly decreased at 20min after ischemia, but it declined progressively 2h after reperfusion, which lasted for 7 days. L4Mg decreased significantly at 20min after ischemia, resumed at 12h after reperfusion and decreased again at 24-48h. Secondary spinal cord ischemic injury and dysfunction are closely related.