Novel derivative of Danshensu acts as anti-thrombotic agent for modulation of protein disulfide isom

• 作 者: Guo-zhenCUI Lu-chenSHAN LinGUO
• 机 构: StateKeyLaboratoryofQualityResearchinChineseMedicineandInstituteofChineseMedicalSciencesUniversityof
• 出 处: 中国药理学与毒理学杂志
• 发表日期: 2015年S1期
• 关键词: ANTI-PLATELET ERp57 DANSHENSU DERIVATIVE ADTM anti-platelet ERp57 Danshensu deri
• 基金项目: The project supported by National Natural Science Foundation of China(81403139)； Research Committee of the University of Macau(MYRG2015-00161-ICMS-QRCM)

OBJECTIVE To identify the specific targets of a novel derivative of Danshensu ADTM as the protein disulfide isomerase(PDI)family proteins including ERp57.To further investigate the underlying mechanism of ADTM to modulate ERp57 to regulate platelet functi