Optimal timing for the oral administration of DaCheng-Qi decoction based on the pharmacokinetic and

• 作 者: Yu-Mei Zhang Lin Zhu Xian-Lin
• 机 构: DepartmentofIntegrativeMedicine,DigestiveSystemDepartment,DepartmentofIntegrativeMedicine,Department
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年39期
• 关键词: Da-Cheng-Qi 煎 尖锐胰腺炎 Pharmacokinetics 口头的 dosing 时间 药效学 Da-Cheng-Qi decoction Ac
• 基金项目: Supported by the National Natural Science Foundation of China,No.81374042,No.81370091 and No.81603480

AIM To identify the optimal oral dosing time of Da-Cheng-Qi decoction(DCQD) in rats with acute pancreatitis(AP) based on the pharmacokinetic and pharmacodynamic parameters.METHODS First, 24 male Sprague-Dawley rats were divided into a sham-operated group