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目的了解南京市数十家医疗单位的临床用血质量安全状况,预防经采供血途径感染艾滋病病毒(HIV)。方法从国家《艾滋病综合防治数据信息系统》中,下载南京市2000-2014年报告的样本来源为无偿献血人员的HIV感染病例数据库,用Excel 2003、SPSS 18.0软件汇总分析。结果南京市数十家医疗单位的临床用血来源于南京市血液中心和江苏省血液中心两家采供血机构,2000-2014年全市采供血系统筛查无偿献血员1 953012人份,发现HIV抗体阳性176例,阳性检出率平均9.01/10万,由2000年的1/10万上升至2014年的20.17/10万,呈逐年上升趋势。176例HIV阳性献血员中,男164例,女12例;汉族169例(96.02%);平均27.73岁(18~51岁);其中20~34岁组135例(76.70%),未婚者115例(65.34%),已婚者43例(24.43%),离异或丧偶者15例(8.52%);现住址南京市者107例(60.80%);大专以上88例(50.00%),高中48例(27.27%),初中26例(14.77%);学生36例(20.45%),干部职员32例(18.18%),商业服务29例(16.48%)。同性性传播88例(50.%),异性性传播66例(37.50%)。2012-2014年发现的81例HIV阳性献血者,男男性行为感染54例(占66.67%)。结论南京市无偿献血员中HIV感染人数及阳性检出率均呈逐年上升趋势,以未婚、低龄、男男性行为传播为主。需加强人群的宣传教育、行为干预等措施,阻断HIV从采供血途径向受血人群的传播。
Objective To understand the quality and safety of clinical blood in dozens of medical units in Nanjing and to prevent the infection of HIV by blood and blood supply. Methods From the national “Integrated AIDS Prevention and Control Information System”, the sample source of Nanjing 2000-2014 report was downloaded from the database of HIV infection cases of unpaid blood donors. The data were aggregated with Excel 2003 and SPSS 18.0 software. Results The clinical blood supply of dozens of medical units in Nanjing came from two blood collection and supply institutions in Nanjing Blood Center and Jiangsu Provincial Blood Center. From 1995 to 2000, 1,930,012 blood donors were screened in the city for blood donation and blood donation system. HIV antibody was found Positive 176 cases, the positive detection rate of an average of 9.01 / 100 000, from 1 in 10 million in 2000 rose to 20.17 / 10 million in 2014, showing an upward trend year by year. Of the 176 HIV-positive donors, 164 were males and 12 females, 169 were Han (96.02%), with an average age of 27.73 years (18-51 years), 135 (76.70% (65.34%) were married, 43 (24.43%) were married, 15 (8.52%) were divorced or widowed, 107 (60.80%) were present in Nanjing, 88 (50.00% (27.27%), 26 junior high school (14.77%), 36 students (20.45%), 32 cadres (18.18%) and 29 commercial services (16.48%). 88 (50%) were homosexual transmission and 66 (37.50%) were heterosexual transmission. 81 HIV-positive donors were found in 2012-2014, and 54 cases were male MSM (66.67%). Conclusions The number of HIV infection and the positive detection rate of unpaid blood donors in Nanjing all showed an increasing trend year by year. The prevalence of unmarried, young men and male sex workers was the highest. It is necessary to step up publicity and education of the population, behavior intervention and other measures to stop the spread of HIV from the blood collection and supply channels to the blood recipients.