Controlled acid hydrolysis and kinetics of flavone C-glycosides from trollflowers

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:cxycsnf
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Acid hydrolysis mechanisms of orientin-2“-O-galactopyranoside(OGA),orientin and other flavone C-glycosides in the trollflowers[Trollius chinensis Bunge) were studied in this report for the first time.Hydrolysis parameters including temperature,acidity,solvent and reaction time were comprehensively investigated.OGA could be hydrolyzed to orientin,followed by an isomerization to isoorientin via a reversible Wessely-Moser rearrangement reaction under stronger acidic conditions.A first-order kinetic model fitted the hydrolysis process of OGA well.Under the optimal hydrolysis conditions of 80 ℃,1.0 mol/L H~+ and 7 h reaction time,about 77%OGA was transformed to orientin with no detectable isoorientin.These results could be helpful for better understanding of the acid hydrolysis kinetics of flavone C-glycosides,as well as the preparation of these valuable components under controlled acid hydrolysis conditions. Acid hydrolysis mechanisms of orientin-2 ”- O-galactopyranoside (OGA), orientin and other flavone C-glycosides in the trollflowers [Trollius chinensis Bunge] were studied in this report for the first time. Hydrolysis parameters including temperature, acidity, solvent and reaction time were comprehensively investigated. OA could be hydrolyzed to orientin, followed by an isomerization to isoorientin via a reversible Wessely-Moser rearrangement reaction under enhanced acidic conditions. A first-order kinetic model fitted the hydrolysis process of OGA well. Unit the optimal The hydrolysis conditions of 80 ° C, 1.0 mol / LH ~ + and 7 h reaction time, about 77% OGA was transformed to orientin with no detectable isoorient. These results could be helpful for better understanding of the acid hydrolysis kinetics of flavone C-glycosides, as well as the preparation of these valuable components under controlled acid hydrolysis conditions.
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