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采用激光衍射法检测３０例脑梗塞病人和３０例同年龄正常人的红细胞变形指数（ＤＩ），发现在２００ｄｙｎ／ｃｍ２剪切力下，病人组ＤＩ值较正常对照组明显降低；同时还测定了两组红细胞膜脂质成分—膜胆固醇（Ｃｈ）、磷脂（Ｐｌ），二者比值（Ｃｈ／Ｐｌ）及血浆脂质等成分。结果膜Ｃｈ、Ｃｈ／Ｐｌ明显高于后者，血浆ＨＤＬ－Ｃ、ＡｐｏＡ－Ｉ明显降低，ＡｐｏＢ明显升高，而血总胆固醇（ＴＣ）无升高。相关分析发现，ＤＩ值与Ｃｈ／Ｐｌ呈负相关。膜Ｃｈ与ＨＤＬ－Ｃ、ＡｐｏＡ－Ｉ呈负相关，与ＡｐｏＢ呈高度正相关。
The laser diffraction method was used to detect the erythrocyte deformability index (DI) of 30 patients with cerebral infarction and 30 normal subjects of the same age. The results showed that under the 200dyn / cm2 shear stress, the DI value of the patient group was significantly lower than that of the normal control group Two groups of lipid components of the erythrocyte membrane - membrane cholesterol (Ch), phospholipid (Pl), the ratio (Ch / Pl) and plasma lipid composition. Results The membrane Ch, Ch / Pl was significantly higher than the latter, plasma HDL-C, ApoA-I decreased significantly, ApoB increased significantly, while the blood total cholesterol (TC) did not increase. Correlation analysis showed that DI value was negatively correlated with Ch / Pl. Membrane Ch was negatively correlated with HDL-C and ApoA-I, and positively correlated with ApoB.