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目的 回顾分析急性中毒患者合并感染情况及其预防效果。方法 选择1999年5月～2001年5月期间在本院急诊的47例急性中毒患者的临床资料,分析合并感染情况,并与非感染者对比分析其临床特点。结果 急性中毒合并感染患者为17例,占36.2％。昏迷合并感染组(14例)比非感染组(26例)平均昏迷时间长[(39.1±26.0)与(24.4±16.7)h],两组间差异有显著性(P<0.05)。抗生素预防用药者中,昏迷合并感染组(6/14,42.9％)低于非感染组(20/26,76.9％)。结论对于急性中毒合并昏迷患者,应及早应用抗生素预防感染。
Objective To retrospectively analyze the combined infection and its prevention in patients with acute poisoning. Methods Clinical data of 47 acute poisoning patients in our hospital from May 1999 to May 2001 were selected to analyze the co-infection status and to compare the clinical features with non-infected patients. Results Acute poisoning patients with infection in 17 cases, accounting for 36.2%. The coma coexisting group (14 cases) had longer coma than those in the non-infected group (39.1 ± 26.0) and (24.4 ± 16.7) h respectively. There was a significant difference between the two groups (P <0.05). Antibiotic prophylaxis in patients with coma infection group (6 / 14,42.9%) was lower than non-infected group (20 / 26,76.9%). Conclusion For acute poisoning patients with coma, antibiotics should be used as early as possible to prevent infection.