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作者近来对前房的胚胎学,特别是源于神经嵴的细胞对角膜、小梁网和虹膜发育的作用进行了研究,认为神经嵴细胞在眼内和眼周围组织及其他结构的形成中起主要作用。用一种新的细胞标记系统研究了神经嵴细胞的移行。此标记系统为日本鹑细胞核内发现的一大团染色质,这与在鸡胚细胞发现的较弥散的染色质不同。将鹑胚神经嵴组织片移植于鸡胚神经嵴处。因为每次细胞分裂时,鹑的染色质均行复制且不被稀释,故可看到这些细胞的移行并能确定其最终位置。鹑神经嵴细胞出现于角膜内皮、小梁网内皮和虹膜基质细胞中,即在晶体与角膜上皮之间的结缔组织均发源于神经嵴。这些细胞构成一连续层,从角膜内皮延伸至小梁网内皮及虹膜前表面。在人妊娠7至8月间,此细胞层不再连续,这一点关系于房水排出易度的增加。有或无房角镜下可见改变的某些先天性青光
The authors have recently performed an investigation of the effects of embryonic development in the anterior chamber, particularly of neural crest-derived cells, on the development of the cornea, trabecular meshwork and iris, suggesting that neural crest cells play a role in the formation of intraocular and periocular tissues and other structures main effect. A new cell labeling system was used to study the migration of neural crest cells. This marker system is a large group of chromatin found in the Japanese quail nucleus, which is different from the more diffuse chromatin found in chicken embryo cells. The quail embryo neural crest tissue transplanted in the chick embryo neural crest. Because each time a cell divides, the quail’s chromatin replicates and is not diluted, so you can see the migration of these cells and determine their final location. Quail neural crest cells appear in the corneal endothelium, trabecular meshwork and iris stromal cells, that is, the connective tissue between the lens and the corneal epithelium originates from the neural crest. These cells form a continuous layer extending from the corneal endothelium to the trabecular meshwork endothelium and the anterior iris surface. In the seventh trimester of pregnancy between August and August, this cell layer is no longer continuous, which is related to the ease of aqueous humor discharge increased. Some congenital glaucoma visible with or without gonioscopic changes