论文部分内容阅读
目的 研究慢性胃炎胃黏膜肠上皮化生患者血清中微量元素的变化及该变化与幽门螺杆菌 ( HP)感染的关系。方法 慢性胃炎肠上皮化生患者 HP阳性组 (简称 HP阳性组 ) 72例 ,HP阴性组 33例 ,用原子吸收光谱仪对其血清中微量元素进行测定。结果 慢性胃炎胃黏膜肠上皮化生患者血清铜、镍、硒均低于正常 ,但此变化在 HP阳性组和 HP阴性组之间无显著性差异 ( P >0 .0 5)。结论 慢性胃炎胃黏膜肠上皮化生病人存在着微量元素代谢紊乱 ,血清中铜、镍、硒低于正常 ,但此变化与 HP感染无相关性。
Objective To study the changes of serum trace elements in patients with chronic gastritis and gastric mucosa intestinal metaplasia and the relationship between the changes and Helicobacter pylori (HP) infection. Methods Seventy-two HP positive patients (HP positive group) and 33 negative patients (HP negative group) were enrolled in this study. The levels of trace elements in serum were determined by atomic absorption spectrometry. Results The serum levels of copper, nickel and selenium in patients with chronic gastritis and gastric mucosa intestinal metaplasia were all lower than those in normal subjects. However, there was no significant difference between HP positive group and HP negative group (P> 0.05). Conclusion There is disorder of trace elements metabolism in patients with chronic gastritis and gastric mucosa intestinal metaplasia. The contents of copper, nickel and selenium in serum are lower than normal, but there is no correlation between these changes and HP infection.