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[目的]探讨医院内真菌感染现状及流行病学特征,为临床真菌感染的预防和治疗提供理论依据。[方法]收集临床真菌感染患者标本,进行分离、鉴定。并从患者年龄、标本来源、病原菌种类、科室分布等方面进行流行病学分析。[结果]收集临床假丝酵母感染标本209例。主要来源于呼吸内科(61.2%),以痰标本的真菌分离率最高(82.8%)。分离出的病原菌以白假丝酵母所占比例最高(72.2%),依次为热带假丝酵母(12.5%)、光滑假丝酵母(8.6%)、克柔假丝酵母(2.4%)、其他假丝酵母(4.3%)。60岁以上老年患者占真菌感染人数的83.7%。[结论]应高度重视医院内真菌感染,加强易受侵袭性真菌感染患者的病原学监测,对真菌感染的高危人群应进行积极的预防。
[Objective] To investigate the status and epidemiological characteristics of fungal infections in hospitals and provide a theoretical basis for the prevention and treatment of clinical fungal infections. [Method] The specimens of patients with clinical fungal infection were collected, separated and identified. The epidemiological analysis was carried out from the aspects of patient’s age, specimen source, pathogen species and departmental distribution. [Result] 209 cases of clinical Candida infection were collected. The main source of respiratory medicine (61.2%), sputum specimens of the highest fungal isolation rate (82.8%). Candida albicans accounted for the highest proportion (72.2%) of pathogenic bacteria isolated, followed by Candida tropicalis (12.5%), Candida glabrata (8.6%), Candida krusei (2.4% Yeast (4.3%). Elderly patients over the age of 60 accounted for 83.7% of the number of fungal infections. [Conclusion] The hospital should pay great attention to the fungal infection and strengthen the etiological monitoring of the patients who are susceptible to invasive fungal infection. Active prevention should be given to the high risk groups of fungal infection.