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目的 :观察立止血 (Reptilase ,Re)对广泛全宫切除手术中失血量及用血量的影响。方法 :选择行广泛全宫切除手术病人 30例 ,随机分为两组分别于切皮前 1 0min静注Re2 0 0 0U ,并以Re 1 0 0 0U静脉滴注维持 (R组 ,n =1 5 )及相应给予Re溶剂作空白对照 (C组 ,n=1 5 ) ;记录术中失血量、用血量、应用麻黄素次数及术中、术后血尿发生情况。结果 :R组术中失血量、用血量、应用麻黄素次数及术中、术后血尿发生率均低于C组 (P <0 .0 5～ 0 .0 1 ) ;手术时间也略低于C组。结论 :Re术中应用立止血效果确切 ,能明显减少手术失血量及用血量 ,相应输血并发症降低 ;手术时间也有所缩短 ,值得推广应用
Objective: To observe the effect of reptilase (Re) on blood loss and blood loss in a total hysterectomy. Methods: Thirty patients underwent a total hysterectomy were randomly divided into two groups: Re 2 000 U at 10 minutes before skin incision, and Re 1 0 0 0 U intravenously (Group R, n = 1 5), and the corresponding Re solvent for the blank control (C group, n = 15); record intraoperative blood loss, blood use, ephedrine application times and intraoperative and postoperative hematuria. Results: The intraoperative blood loss, blood volume, frequency of application of ephedrine and intraoperative and postoperative hematuria rates in group R were lower than those in group C (P <0.05-0.01). The operative time was also slightly lower In group C Conclusions: The effect of using standing blood in Re is exact, which can obviously reduce blood loss and blood volume of operation, and reduce the complication of blood transfusion. The operation time also shortened, which is worth popularizing and applying