论文部分内容阅读
目的观察壳聚糖抗菌喷剂治疗烧伤残余创面的疗效。方法 84例烧伤后期残余创面的患者随机均分为试验组和对照组。试验组创面用生理盐水清洗后将壳聚糖抗菌喷剂直接喷涂创面,每天2次;对照组创面消毒后仅单层碘伏纱布覆盖行半暴露疗法。10d为1个疗程。比较两组的疗效及细菌学情况,并采用视觉模拟评分法(VAS)对患者创面总体疼痛感觉进行评价。结果试验组创面治愈率、总有效率和细菌清除率分别为66.7%、88.1%和89.5%,均高于对照组的40.5%、64.3%和70.3%(P<0.01)。试验组创面换药30例患者感轻微疼痛,VAS评分为≤3分;对照组27例创面换药时感到明显疼痛,VAS评分为3-6分(P<0.01)。结论壳聚糖抗菌喷剂可以显著促进烧伤残余创面愈合,明显减轻患者的疼痛。
Objective To observe the curative effect of chitosan antibacterial spray for the treatment of residual burn wounds. Methods Eighty-four patients with post-burn residual wounds were randomly divided into experimental group and control group. The wounds of experimental group were sprayed with chitosan antibacterial spray directly on the wound surface with saline twice a day, while the wounds in the control group were treated with semi-exposure therapy with single layer of iodophor gauze after disinfection. 10d for a course of treatment. The curative effect and bacteriological status of the two groups were compared. The visual analogue scale (VAS) was used to evaluate the overall pain sensation of the patients’ wounds. Results The wound healing rate, total effective rate and bacterial clearance rate of the experimental group were 66.7%, 88.1% and 89.5%, respectively, which were all higher than those of the control group (40.5%, 64.3% and 70.3%, P <0.01). Thirty patients in the experimental group had mild pain, VAS score was ≤3, while those in the control group had obvious pain when dressing was changed. The VAS score was 3-6 (P <0.01). Conclusion Chitosan antibacterial spray can significantly promote wound healing of burn wounds and significantly reduce the pain of patients.