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目的分析急性细菌性感染性腹泻患者的治疗过程中应用左氧氟沙星治疗的临床效果。方法 54例急性细菌性感染性腹泻患者,采用抽签法分为观察组与对照组,每组27例。给予对照组患者头孢曲松钠治疗,给予观察组患者左氧氟沙星治疗,对比分析两组患者治疗后的疗效及白细胞增多、白细胞、脓细胞、红细胞水平。结果两组患者经过5 d治疗后,观察组患者的显效、有效、无效例数分别为20、6、1例,总有效率为96.30%,对照组患者的显效、有效、无效例数分别为10、8、9例,总有效率为66.67%,观察组患者的临床总有效率高于对照组,差异具有统计学意义(χ~2=7.85,P<0.05)。观察组患者的白细胞增多、白细胞、脓细胞、红细胞例数分别为1、1、0、0例,对照组患者的白细胞增多、白细胞、脓细胞、红细胞例数分别为9、8、4、5例,观察组患者各实验室检查指标情况均优于对照组,差异均具有统计学意义(χ~2=7.8545、6.5333、4.3200、5.5102,P<0.05)。结论在急性细菌性感染性腹泻患者的治疗过程中应用左氧氟沙星治疗的临床疗效较为显著,值得临床推广。
Objective To analyze the clinical effect of levofloxacin in the treatment of patients with acute bacterial infectious diarrhea. Methods A total of 54 patients with acute bacterial infectious diarrhea were divided into observation group and control group by random sampling, with 27 cases in each group. The patients in the control group were treated with ceftriaxone sodium and the patients in the observation group were treated with levofloxacin. The curative effect and leukocytosis, white blood cells, pus and erythrocyte levels were compared between the two groups after treatment. Results After 5 days of treatment, the effective and invalid cases in the observation group were 20.6 and 1 cases, respectively, the total effective rate was 96.30%. The effective, effective and invalid cases in the control group were The total effective rate was 66.67% in 10, 8 and 9 cases. The total effective rate in observation group was higher than that in control group (χ ~ 2 = 7.85, P <0.05). Observation group patients with leukocytosis, white blood cells, pus, erythrocyte cases were 1,1,0,0 cases, the control group of patients with leukocytosis, white blood cells, pus, red blood cell count were 9,8,4,5 Cases, the observation group of patients with laboratory test indicators were better than the control group, the differences were statistically significant (χ ~ 2 = 7.8545,6.5333,4.3200,5.5102, P <0.05). Conclusion The clinical efficacy of levofloxacin in the treatment of patients with acute bacterial infectious diarrhea is more significant and worthy of clinical promotion.