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发表在国际杂志Nature Medicine上的一篇研究论文中,来自美国华特瑞陆军研究院的研究人员通过研究表示,相比感染单一HIV-1菌株的患者而言,感染多种HIV-1突变体的患者或预后表现较差。文章中,研究者对来自泰国的两项重要的HIV疫苗试验-HVTN 502和RV144中大量的样本进行分析,以此来评估是否原始的HIV-1病毒群体的遗传特性会影响患者临床预后的标志物。随后研究者检测了样本中的病毒载量以及CD4 T细胞的计数情况;研究者指出,所有的研究都
In a research paper published in the journal Nature Medicine, researchers from the Walter Army Research Institute in the United States said through studies that many HIV-1 mutants were infected compared to patients infected with a single HIV-1 strain Of patients or poor prognosis. In the article, the researchers analyzed a large number of samples from two major HIV vaccine trials in Thailand, HVTN 502 and RV144, to assess whether the genetic profile of the original HIV-1 viral population would affect the patient’s clinical prognosis Things. The researchers then examined the viral load in the sample and the count of CD4 T cells; the investigators noted that all the studies