论文部分内容阅读
抗癫癎新药香荚兰醛鉴定会于1月15日在江苏省卫生厅组织下召开。 1965年,南京药学院在研究天麻工作中受到启发,合成具有抗癎作用的香荚兰醛,其化学结构与目前市场上大量供应作食用香料的香兰素相同。在江苏省卫生厅领导下,该院经过多年与有关单位协作,完成了从食用香兰素制成药用香荚兰醛的生产工艺、药理、毒理、质量标准、药物代谢动力学等研究。经7个临床单位、291例(单用香荚兰醛片184例,用其它抗癫癎药治疗无效加用香荚兰醛片者107例)临床观察结果表明,对癫癎病总有效率达74.2%,显效率48.8%。单用香荚兰醛片治疗的184例中,对癫癎小发作总有效率86.1%,显效率
The anti-epileptic new drug vanillin aldehyde appraisal meeting was held on January 15 under the organization of the Jiangsu Provincial Department of Health. In 1965, the Nanjing Institute of Pharmacy was inspired to study the gastrodia and synthesize vanillin aldehyde with anti-carrageenan effect. Its chemical structure is the same as that of vanillin, which is widely used as a flavoring in the market. Under the leadership of the Jiangsu Provincial Department of Health, after many years of collaboration with relevant agencies, the Institute completed the research on the production technology, pharmacology, toxicology, quality standards, and pharmacokinetics of medicinal vanilla aldehyde produced from edible vanillin. . After 7 clinical units and 291 patients (a single use of geranyl aldehyde tablets in 184 cases, 107 patients treated with other antiepileptic drugs who failed to add vanilloid tablets) showed that the total epilepsy was effective Up to 74.2%, significant efficiency of 48.8%. In the 184 patients treated with vanilloid alone, the total effective rate of epilepsy was 86.1%.