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1977年意大利学者 Rizzetto 等用间接免疫荧光法检测乙型肝炎病毒(HBV)时,发现了一种新的抗原,当时称δ因子。此后,各国学者对其进行了广泛深入的研究。1984年,鉴于对δ因子的特性已充分了解,Rizzetto 等建议,将δ因子及其抗原、抗体和相关肝炎,分别命名为δ肝炎病毒(HDV)、δ抗原(HDAg)、δ抗体(抗—HD)和δ肝炎(HD)。我国称丁型肝炎。病原学从急性感染的猩猩和人的血液中已分离到 HDV。研究证实,HDV 直径为35～37nm,在氯化铯中的浮密度为1.24～1.28g/cm~2,HDV 内部由 HDV 基因组和 HDAg 组成,
1977 Italian scholar Rizzetto and other indirect immunofluorescence detection of Hepatitis B virus (HBV), found a new antigen, then called δ factor. Since then, scholars from various countries carried out extensive and in-depth research. In 1984, Rizzetto et al. Proposed that the δ-factor and its antigens, antibodies and related hepatitis should be named as hepatitis D virus (HDV), delta antigen (HDAg), delta antibody (anti- HD) and delta hepatitis (HD). My country called hepatitis D. Etiology HDV has been isolated from acutely infected orangutans and human blood. The study confirmed that the HDV diameter of 35 ~ 37nm, the cesium chloride in the floating density of 1.24 ~ 1.28g / cm ~ 2, the internal HDV HDV genome and HDAg composition,