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第四部分抗菌药物的联合疗法、配伍禁忌文献中所介绍的各种有效联合(表1),大多系依据体外联合药敏试验的结果而制订,经动物实验证实者很少,而经临床应用获得明确结论者则为数更少。单一药物的药敏结果与临床疗效的符合率较高,两者的关系也比较肯定,联合用药则可因药物代谢动力学不同,药物间相互作用等因素的影响,致使药敏结果与临床疗效之间出现较大的差异。
The fourth part of the antimicrobial drug combination therapy, incompatibility compatibility introduced in the literature of the various effective combination (Table 1), mostly based on the results of in vitro combined susceptibility test developed by animal experiments to prove that few, and clinical application The number of those who reach a clear conclusion is even smaller. Single drug susceptibility results and clinical efficacy in line with the higher rate of the relationship between the two is more affirmative, the combination can be due to different pharmacokinetics, drug interactions and other factors, resulting in drug susceptibility results and clinical efficacy There is a big difference between.