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目的探讨肺磨玻璃样病变(GGO)侵袭性的相关因素。方法 47例CT征象为肺部磨玻璃影的肺腺癌患者,按照GGO实性成分最大径与肺窗测GGO最大径之比(R表示)分组,R≥0.5作为观察组(32例),R<0.5作为对照组(15例)。对比两组患者的临床、影像、病理资料,判断其侵袭性。结果两组患者病灶部位、直径、形状以及边界是否清晰情况比较差异无统计学意义(P>0.05);观察组的边缘分叶和(或)毛刺比例、胸膜凹陷征以及空泡征比例明显高于对照组,差异具有统计学意义(P<0.05);观察组患者的吸烟史和感染史比例(21例和19例)高于对照组(5例和6例),差异有统计学意义(P<0.05)。两组患者淋巴结转移及脉管癌栓比例比较差异无统计学意义(P>0.05);观察组病理分期及胸膜侵犯率高于对照组,差异有统计学意义(P<0.05)。结论 GGO的病灶实性比例越高肿瘤侵袭性越强,CT征象对判断肿瘤侵袭性具有重要价值。
Objective To investigate the related factors of invasiveness of lung gliomas (GGO). Methods Forty-seven patients with lung adenocarcinoma who underwent vitreous lung scintigraphy were divided into two groups according to the ratio of the maximum diameter of GGO to the maximum diameter of lung GGO (R), R≥0.5 as the observation group (32 cases) R <0.5 as a control group (15 cases). Compare the two groups of patients with clinical, imaging, pathological data to determine the invasiveness. Results There was no significant difference in lesion location, diameter, shape and border between the two groups (P> 0.05). The proportion of border lobe and / or burr, pleural indentation and vacuolar sign in the observation group was significantly higher (P <0.05). The smoking history and infection history in the observation group (21 cases and 19 cases) were higher than those in the control group (5 cases and 6 cases), the difference was statistically significant (P < P <0.05). There was no significant difference in lymph node metastasis and vascular thrombus between the two groups (P> 0.05). The pathological stage and pleural invasion rate in the observation group were significantly higher than those in the control group (P <0.05). Conclusion The higher the proportion of solid lesions in GGO, the higher the aggressiveness of the tumor. The CT signs have important value in judging tumor invasiveness.