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附睾是产生肉毒硷的一个丰富源泉。肉毒硷是通过雄性激素控制下,由上皮细胞所合成。Wet-terrauer等最早注意到人精液浆的肉毒硷浓度和精子数量之间呈正相关。与此同时,Tremblay等报告了由附睾所大量分泌的另一种化合物,为精子成熟提供最适宜能量的中性α—1,4糖甙酶,它和精子密度及活动力也呈正相关。鉴于这两种化合物都以其特定的机理参与了附睾精子的成熟过程:肉毒硷提高脂肪酸的氧化作用,而α—1,4糖甙酶催化
Epididymis is a rich source of carnitine. Carnitine is synthesized by epithelial cells under the control of androgens. Wet-terrauer et al. First noted a positive correlation between the concentration of carnitine in human seminal plasma and sperm count. In the meantime, Tremblay et al. Reported another compound secreted by the epididymis in large quantities to provide the most energetic neutral α-1,4 glucosidase for sperm maturation, which is also positively correlated with sperm density and motility. Since both compounds are involved in the maturation of epididymal sperm by their specific mechanism: carnitine enhances the oxidation of fatty acids, whereas alpha-1,4 glucosidase catalyzes