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目的:观察恶性心包积液心包穿刺置管引流并实施腔内化疗的疗效及安全性。方法:在48例恶性心包积液中,19例有心包填塞症状者行心包穿刺置管并腔内化疗。29例无心包填塞症状未行腔内治疗的恶性心包积液患者均接受了全身化疗。结果:腔内化疗完全缓解9例,好转8例,无效1例,有效率89.5%。未行腔内化疗的恶性心包积液患者接受了全身化疗,有效率34.5%。结论:在心包积液量较大时,应首选腔内注药治疗,安全有效,不良反应小。
Objective: To observe the efficacy and safety of pericardial effusion pericardiocentesis by catheterization and endovascular chemotherapy. Methods: In 48 cases of malignant pericardial effusion, 19 cases had symptoms of pericardiocentesis by pericardiocentesis and intracavitary chemotherapy. Twenty-nine patients with malignant pericardial effusion who did not receive endovascular treatment of cardiac tamponade received systemic chemotherapy. Results: 9 cases were completely relieved by endovascular chemotherapy, 8 cases improved, 1 case was ineffective, and the effective rate was 89.5%. Patients with malignant pericardial effusion undergoing endovascular chemotherapy received systemic chemotherapy with an effective rate of 34.5%. Conclusion: When the volume of pericardial effusion is larger, intracavitary injection should be the preferred treatment, which is safe and effective with little adverse reactions.