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索他洛尔延长动作电位和有效不应期,属Ⅲ类抗心律失常药物,能恢复和保持窦性节律。此外,它具有β-肾上腺能受体阻滞作用,也可作为Ⅱ类抗心律失常药物,能控制房颤时的心室率,尤其在体力运动血浆儿茶酚胺浓度升高时。作者在本研究中旨在评估单用地高辛控制慢性房颤心室率不满意时,
Sotalol extended action potential and effective refractory period, is a class III anti-arrhythmic drugs, can restore and maintain sinus rhythm. In addition, it has β-adrenergic receptor blockade, but also as Class Ⅱ anti-arrhythmic drugs, can control ventricular rate during atrial fibrillation, especially in physical exercise plasma catecholaminergic concentrations. In this study, the authors aimed to assess the ventricular rate of chronic atrial fibrillation with digoxin alone was not satisfied,