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Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-contin-uum generated by coupling femtosecond pulses from a commercial Ti:sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 μm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample,only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated,showing great potential for biomedical application.
Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-contin-uum generated by coupling femtoseconds pulses from a commercial Ti: sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to The sensitivity of OCT system was 108 dB with incident light power of 3 mW at sample, only 7 dB below the theoretical limit. Sub-band OCT imaging was also demonstrated, showing great potential for biomedical application.