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多效性细胞活素——白介素-10(一种18.7Kda多肽)原来被认为是Th2细胞亚组的产物,现今始知其具有前景的免疫抑制特性。这些特性包括通过单核细胞和多形白细胞(二者处于蛋白质和mRNA水平,并阻止具有特异抗原的T细胞增生)所产生的前炎性细胞[干扰素-γ,肿瘤坏死因子-α
The pleiotropic cytokine interleukin-10, an 18.7 KDa polypeptide, was originally thought to be a product of a subset of Th2 cells, now known for its promising immunosuppressive properties. These include pro-inflammatory cells produced by monocytes and polymorphonuclear leukocytes, both at protein and mRNA levels, and preventing T cell proliferation with specific antigens [interferon-gamma, tumor necrosis factor-alpha