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心血管疾病(CVD)是1型糖尿病的主要死因之一。近年来，糖尿病诊疗技术取得了巨大的进步，其对1型糖尿病CVD结局的影响值得深入研究。2020年5月，n J Clin Endocrinol Metab杂志发表了一篇题为《1型糖尿病的心血管疾病风险因素：来自前瞻性真实世界1型糖尿病交流登记系统的发现》的文章[Shah VN, Bailey R, Wu M, et al. Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry[J]. J Clin Endocrinol Metab, 2020，105(5)：e2032-e2038. DOI: 10.1210/clinem/dgaa015.]，在获得原文刊发杂志同意并授权后，本文对该文进行中文编译。该文对来自美国最大的成年1型糖尿病患者登记系统——1型糖尿病交流门诊网络登记(T1D Exchange Clinic Network Registry)的8 727例1型糖尿病患者CVD的发病率和相关风险因素进行了前瞻性观察性研究，中位随访期5.3年。结果显示，平均随访4.6年后，成年1型糖尿病患者的CVD发病率为3.7%。HbAn 1C、高血压、血脂异常以及糖尿病肾病是成年1型糖尿病CVD的重要风险因素。n “,”Cardiovascular disease (CVD) remains a leading cause of mortality in type 1 diabetes. Remarkable progress has been made in some aspects of diabetes care over the last decade, which warrants furthering investigation on CVD outcomes. This paper is the Chinese translation of “Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry” , published on n J Clin Endocrinol Metab [Shah VN, Bailey R, Wu M, et al. J Clin Endocrinol Metab, 2020, 105(5): e2032-e2038. DOI: 10.1210/clinem/dgaa015.] in May 2020, with the permission from the original journal. The research enrolled 8 727 participants without known CVD from The T1D Exchange Clinic Network Registry, the largest registry of adults with type 1 diabetes in the United States, prospectively studying incidence and risk factors for CVD in adults with type 1 diabetes over a median of 5.3 years. It was found that the incidence of CVD in adults with type 1 diabetes was 3.7% over a mean follow-up of 4.6 years. Multiple risk factors including HbAn 1C, hypertension, dyslipidemia, and diabetic nephropathy were associated with the increase in odds of CVD among adults with type 1 diabetes.n