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近年来,随着细胞动力学的研究,急性白血病(AL)的治疗取得了重要进展,尤其是急性淋巴细胞性白血病(ALL)完全缓解率(CR)可达90％。现将我院资料报告如下: 我院自1974年7月～1984年6月共收ALL79例,己用满一疗程的67例中CR31例,CR率46.27％,男性20例,女性11例,年龄最小12岁,最大60岁,其中12～29岁年龄组最多,占26例,可见年龄愈小,CR率愈高。基本方案以COAPT为主,个别病人加用6～mP,L-ASP,用法为VCR2mg, iv, 1/w, CTX200mg, iv: q.o.d, Ara-C100mg, iv.q.o.d(二药交替应用),Prednisone 10mg, Tid,连用5～7天,疗程最后一天MTX10～15mg+氟美松5mg椎管内注射,上药共用7～9天为一疗程,休
In recent years, with the study of cell kinetics, important progress has been made in the treatment of acute leukemia (AL), in particular, the complete remission rate (CR) of acute lymphoblastic leukemia (ALL) can reach 90%. Our hospital now report as follows: Our hospital from July 1974 to June 1984 received a total of ALL79 cases, has been used for a course of 67 cases of CR31 cases, CR rate was 46.27%, 20 males and 11 females, The youngest 12 years old, maximum 60 years, of which 12 to 29 age group, accounting for 26 cases, showing that the younger the younger the higher the CR rate. The basic protocol was COAPT, with 6 ~ mP and L-ASP for individual patients. The usage was VCR2mg, iv, 1 / w, CTX200mg, iv: qod, Ara-C100mg, iv.qod 10mg, Tid, once every 5 to 7 days, the last day of treatment MTX10 ~ 15mg + 5mg intradermal injection of flumethasone, the drug shared 7 to 9 days for a course of treatment, the rest