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目的 评价雷帕霉素洗脱支架 (CypherTM)的安全及近期有效性。方法 回顾分析 112例接受CypherTM 支架置入术患者的即刻疗效和临床随访结果。结果 112例患者共处理 173处病变 ,置入支架 2 2 7枚 ,其中 132处病变置入15 9枚CypherTM支架。 2处严重钙化病变需辅以高压球囊才充分扩张 ,1处支架近端发生内膜撕裂。其余全部成功置入 ,手术过程及住院期间无严重并发症发生 ,成功率 98 1%。10 4例患者随访 3～ 17个月 ,平均 (7 2± 4 0 )个月 ,无心源性死亡和心肌梗死发生 ,9例患者心绞痛再发 ,其中 5例为普通金属支架内的再狭窄 ,4例为其他分支的新病变。 112例患者中共 2 8例复查了冠状动脉造影 ,CypherTM支架内均无再狭窄。结论 CypherTM支架近期安全有效。
Objective To evaluate the safety and near-term efficacy of the rapamycin-eluting stent (CypherTM). Methods A retrospective analysis of 112 patients undergoing CypherTM stenting in patients with immediate effect and clinical follow-up results. Results A total of 173 lesions were treated in 112 patients. There were 227 cases of stent placement, of which 159 CypherTM stents were placed in 132 lesions. Serious calcification lesions at 2 should be supplemented by high-pressure balloon was fully expanded, a stent proximal endometrial tear. All the others were successfully inserted. No serious complication occurred during the operation and hospitalization, with a success rate of 98.1%. 10 4 patients were followed up for 3 to 17 months with an average of (72 ± 40) months without cardiogenic death and myocardial infarction. Nine patients had recurrence of angina pectoris. Among them, 5 were in-stent restenosis, 4 cases for the other branches of the new lesions. Coronary angiography was reviewed in 28 of 112 patients, with no restenosis within the Cypher stent. Conclusion Cypher stent is safe and effective recently.