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目的 探讨鼻咽癌鼻咽肿瘤体积与T分期的关系。方法 将首程放疗前NPC病人 2 0例的鼻咽MRI扫描资料输入三维治疗计划系统进行鼻咽肿瘤体积计算 ,比较鼻咽肿瘤体积与 1992福州分期、1987香港何氏分期和1997UICC分期T分期的关系。结果 在T1、T2、T3和T4各期中 ,鼻咽肿瘤平均体积 (c )分别为 :1992福州分期 :9.999± 3 .85 4,16.14± 4.176,43 .5 61± 2 2 .846和 45 .2 67± 2 2 .5 13 (F =3 .5 8,P =0 .0 3 7) ;香港何氏分期 :9.999± 3 .85 4,2 8.0 76± 19.3 87和 44 .15 5± 2 2 .915 (F =3 .63 ,P =0 .0 487) ;UICC分期 :9.999± 3 .85 4,2 8.0 76± 19.3 87,45 .0 18± 2 1.63 5和 43 .2 91± 2 6.178(F =2 .2 9,P =0 .118)。结论 1992福州分期和香港何氏分期的鼻咽癌T分期标准 ,能基本反映鼻咽肿瘤的体积大小 ,1997UICC分期的鼻咽癌T分期标准未能反映T分期与鼻咽肿瘤体积大小的相关关系。建议对1992福州分期标准作以下补充 :蝶窦受累归入T3 ,喉咽受累归入T4。随着三维治疗计划系统的普及 ,今后更为准确、更能预测肿瘤预后的肿瘤T分期 ,应考虑加入体积因素。
Objective To investigate the relationship between nasopharyngeal carcinoma volume and T stage of nasopharyngeal carcinoma. Methods Nasopharyngeal MRI scan data of 20 NPC patients before the first course radiotherapy were input to the three-dimensional treatment planning system for nasopharyngeal tumor volume calculation. Nasopharyngeal tumor volume was compared with 1992 Fuzhou staging, 1987 Hong Kong staging and 1997 UICC staging T staging relationship. Results The mean volume of nasopharyngeal tumors (c) in T1, T2, T3 and T4 phases were: 1992 Fuzhou staging: 9.999 ± 3.85 4,16.14 ± 4.176,43.561 ± 22.846 and 45 .2 67 ± 2 2 .5 13 (F = 3.58, P = 0.307); Hong Kong’s Staging: 9.999 ± 3 .85 4,2 8.0 76 ± 19.3 87 and 44 .15 5 ± 2 2 .915 (F = 3.63, P = .0487); UICC staging: 9.999 ± 3 .85 4,2 8.0 76 ± 19.3 87,45 .0 18 ± 2 1.63 5 and 43 .2 91 ± 2 6.178 (F = 2.29, P = 0.118). Conclusions The T stage of nasopharyngeal carcinoma staging 1992 Fuzhou staging and Hong Kong st st pharyngeal staging can basically reflect the size of nasopharyngeal neoplasm. The staging of nasopharyngeal T staging 1997UICC staging failed to reflect the relationship between T staging and nasopharyngeal tumor volume . Proposed 1992 Fuzhou staging criteria for the following additions: sphenoid sinus involvement in T3, T4 involved in the inclusion of laryngopharyngeal. With the popularity of three-dimensional treatment planning system, the future more accurate, more predictable prognosis of tumor T staging, should consider adding volume factors.