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目的 :针对传统方法处理稽留流产时出现的困难及并发症多的难点 ,尝试探讨无创性治疗方法在稽留流产中的效果及可行性。方法 :对 176例符合统计条件确诊为稽留流产者随机分为A ,B ,C三组 ,分别予不同用药方法进行治疗 ,观察疗效、不良反应及其并发症。结果 :米非司酮 +米索前列醇 +己烯雌酚治疗方法完全流产率 95 % ,有效率 10 0 % ,明显优于另外两组 (P <0 0 1) ;排胎时间为 (4 2± 3 6 )h ,显著短于B组 (P<0 0 1) ;无需二次清宫 ,出血少 ,胃肠反应轻微 ,流血时间、月经复潮、月经期无明显差异 ,属正常范围。结论 :米非司酮配米索前列醇 (阴道用者 ) ,加用己烯雌酚治疗稽留流产效果好 ,安全性可靠 ;其次是米非司酮配米索前列醇法 ;大剂量催产素效果较差
Objective: To address the difficulties and complications of traditional abortion in treating aborted abortion, try to explore the effectiveness and feasibility of noninvasive treatment in missed abortion. Methods: A total of 176 patients with confirmed abortion under statistical conditions were randomly divided into three groups (A, B and C). The patients were treated with different methods of treatment, and the curative effect, side effects and complications were observed. Results: The mifepristone + misoprostol + diethylstilbestrol treatment method completely abortion rate was 95%, the effective rate was 100%, significantly better than the other two groups (P <0 01); rowing time was (4 2 ± 3 6) h, which was significantly shorter than that in group B (P <0.01). No secondary clearance, less bleeding, mild gastrointestinal reactions, bleeding time, menstrual flow and menstrual period were no significant differences. Conclusion: Mifepristone with misoprostol (vaginal) plus diethylstilbestrol treatment of missed abortion is effective, safe and reliable; followed by mifepristone with misoprostol; high-dose oxytocin less effective