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近年来由于治疗淋病不规范用药,使淋球菌耐药菌株和变异菌出现。Gnarpe从12%的淋病患者尿道,宫颈中分离出L型淋球菌,以后,不断有L型淋球菌的研究报道。与临床上表现为慢性难治性淋病有非常密切关系。笔者自1995年来收治的66例L型淋球菌感染者均系迁延不愈,症状反复发作的慢性难治性淋病。用中西结合方法治疗获得较为满意疗效。现报告如下。 1 临床资料与方法 1.1 对象 选择临床病人66例按随机化方法分为治疗组,对照组各33例。治疗组:男性20例、女性13例,年龄20~40岁,平均25岁,病程5~24个月,平均11个月。对照组男性22例、女性11例,年龄19~44岁,平均27岁,病程4~18个月,平均12个月,所有病例均反复发作3次以上,有婚外性行为或配偶感染史及其它密切接触史,有尿道感染症状,尿道口分泌物,女性有脓性白带,实验室分泌物培养:L型淋球菌阳性。
In recent years due to treatment of gonorrhea is not standardized medication, so that gonococcal drug-resistant strains and mutants appear. Gnarpe from 12% of gonorrhea urethra, cervix isolated from Neisseria gonorrhoeae, and later, continue to have L gonococcal research reports. And clinically manifested as chronic refractory gonorrhea have a very close relationship. 66 cases of L-type Neisseria gonorrhoeae who were admitted to our hospital in 1995 were chronic refractory gonorrhea with prolonged unhealed symptoms and recurrent symptoms. With the combination of Chinese and Western methods to obtain more satisfactory results. The report is as follows. 1 Clinical data and methods 1.1 Object Selection 66 cases of clinical patients were randomly divided into treatment group and control group of 33 cases. Treatment group: 20 males and 13 females, aged 20 to 40 years old, average 25 years old, duration of 5 to 24 months, an average of 11 months. The control group of 22 males and 11 females, aged 19 to 44 years, mean 27 years, duration of 4 to 18 months, an average of 12 months, all cases were recurrent more than 3 times, with extramarital sex or spouse history of infection And other close contact history, there are symptoms of urinary tract infection, urethral orifice secretions, female purulent vaginal discharge, laboratory secretions culture: L-type Neisseria gonorrhoeae positive.